Micro-dosing refers to the practice of taking small, sub-perceptual amounts of a psychoactive substance, such as LSD or psilocybin, with the intention of improving mood, creativity, or productivity.
The goal of micro-dosing is to achieve a subtle, yet noticeable improvement in well being, without inducing any significant change in perception or thought processes. The goal is to use this small amount on a regular basis without restrictions and maintain the ability to incorporate it in to your daily regime. Most find they can actually function better in their day to day life whether it’s work, play or nurturing relationships.
Psilocybin is a naturally occurring psychedelic substance found in certain species of mushrooms, commonly referred to as "magic mushrooms." It has been used for centuries in traditional indigenous spiritual and medicinal practices.
Psilocybin has been researched since the 1950’s. In recent decades, psilocybin has gained renewed interest as a possible treatment for various mental health conditions, such as depression and anxiety. Clinical research has shown that psilocybin can produce rapid and long-lasting improvements in mood and well-being, as well as increased creativity and spiritual connectedness.
Clinical studies have shown that psilocybin can produce rapid and long-lasting improvements in mood and well-being in patients with depression and anxiety.
Psilocybin has shown potential as a treatment for symptoms of post-traumatic stress disorder (PTSD) in early clinical trials.
Psilocybin can lead to a profound sense of spiritual connection, which can help individuals with depression and anxiety find meaning and purpose in life.
Psilocybin has been shown to increase creativity, problem-solving ability, and divergent thinking in some individuals.
Psilocybin can lead to increased self-esteem and confidence in some individuals, which can be especially helpful for those with low self-worth or body image issues.
Psilocybin has been shown to decrease fear and anxiety, which can be particularly helpful for individuals with phobias or social anxiety disorders.
Psilocybin has been shown to improve the quality of life for individuals with life threatening illnesses, such as cancer, by reducing anxiety and depression and increasing spiritual connection.
Psilocybin has been shown to reduce dependence on alcohol and other substances in some individuals.
Psilocybin can lead to improved relationships with loved ones, as individuals may experience increased empathy and understanding towards others.
Clinical studies have shown that psilocybin can produce rapid and long-lasting improvements in mood and well-being in patients with depression and anxiety.
Psilocybin has been shown to increase acceptance of death in individuals, which can be especially helpful for those with terminal illnesses or those facing death-related fears.
Psilocybin, a naturally occurring compound found in certain species of mushrooms, has been studied for its effects on the nervous system. Studies have found that psilocybin affects the nervous system in a variety of ways, including altering the brain’s chemical balance and influencing the activity of certain parts of the brain. When taken, psilocybin binds to serotonin receptors in the brain, leading to changes in the brain’s chemical balance. This causes an increase in the production of serotonin, a neurotransmitter associated with feelings of well-being, happiness, and relaxation. Additionally, research suggests that psilocybin can also increase the activity of the prefrontal cortex, an area of the brain associated with higher cognitive functions like decision-making and creativity.
Psilocybin, especially in larger (macro) doses, can cause a variety of side effects including: nausea, vomiting, headaches, muscle tension and difficulty in concentrating. These side affects tend to be mild, if any, when micro-dosing and typically temporary. While some of these effects may be beneficial to reset the body, it is important to recognize the potential risks associated with the use of this substance. These effects can be potentially dangerous for individuals with certain preexisting mental health issues. Individuals should be aware of the potential side effects and should consult with a medical professional before taking psilocybin. Additionally, it is important to note that psilocybin is classified as a controlled substance and should be used with caution.
Psychologically, psilocybin is known to produce feelings of euphoria, peace, and well being. It can also reduce anxiety, fear, and depression, while increasing mindfulness and insight. In some cases, it can also induce spiritual experiences, creativity, and enhanced empathy. However, it is important to note that the effects of psilocybin can vary greatly from person to person, and not everyone will have the same experience.
In order to work and integrate in the body, psilocybin is broken down into psilocin. The conversion of psilocybin to psilocin is done by an enzyme in the body known as alkaline phosphatase. This enzyme is found in the liver, intestines, and other organs. It acts on the chemical structure of psilocybin in order to produce psilocin. The enzyme breaks down the chemical structure of psilocybin, specifically the phosphate group attached to the molecule. This breaks the bond between the atomic components of the molecule, allowing the psilocin to be released. The conversion of psilocybin to psilocin is a relatively quick process. It typically takes only a few minutes to complete, depending on the individual's metabolic rate. Once the conversion is complete, the effects of psilocin can be felt within 15-30 minutes.
A micro-dose of psilocybin is a sub-perceptual dose, meaning it is not enough to cause significant alterations in perception, but still high enough to produce subtle changes in mood, thought, and behavior. Micro-dosing is often done with the goal of enhancing creativity, productivity, and general well-being. A macro-dose, on the other hand, is a full or near-full dose that can produce intense, transformative experiences and profound changes in consciousness.
The effects of a macro-dose can last several hours and can include visual and auditory hallucinations, altered perceptions of time and space, and a feeling of detachment from one's normal sense of self. The exact definition of a micro-dose and a macro-dose will vary depending on the individual, but a general guideline is to take around 50-250 milligrams for a micro-dose and 2.5-5.0 grams for a macro-dose of dried psilocybin mushrooms.
Psilocybin is a naturally occurring hallucinogenic compound found in certain species of mushrooms, also known as "magic mushrooms." The use of psilocybin-containing mushrooms has been traced back to prehistoric times in cultures around the world, including Mesoamerican and Native American tribes.
In the mid-20th century, psilocybin gained popularity in Western society as part of the counterculture movement, with individuals such as Timothy Leary and Aldous Huxley promoting its use for spiritual and creative exploration. However, due to the growing concerns about drug abuse and the lack of medical research, psilocybin was classified as a Schedule I substance in the United States in 1970, making it illegal to possess or use.
In the 1990s, a renewed interest in the potential therapeutic benefits of psilocybin led to the formation of the Heffter Research Institute, dedicated to studying the use of psilocybin and other hallucinogens in treating mental illness.
In 2006, a study conducted at the University of Arizona showed that psilocybin could produce long-lasting positive changes in attitudes, moods, and behavior in healthy volunteers.
In 2016, Johns Hopkins University announced the formation of the Center for Psychedelic and Consciousness Research, the first of its kind in the United States, to study the effects of psilocybin and other psychedelics on various psychiatric conditions.
In 2018, the FDA granted "breakthrough therapy" designation to psilocybin therapy for treatment-resistant depression, fast-tracking its development and potential approval as a prescription drug. Recent clinical trials have shown promising results for the use of psilocybin in treating a range of mental health conditions, including depression, anxiety, PTSD, and addiction.
As of 2023, psilocybin remains a Schedule I substance in the United States, but there is a growing movement to decriminalize and legalize its use for medical and therapeutic purposes.
While significant independent and academic research has demonstrated benefits in micro-dosing, micro-dosing is not an FDA-approved practice. Its effects, both positive and negative, are not fully understood by science.